Why the study?
Does familial hypobetalipoproteinemia prevent the development of arterial atherosclerotic lesions?
Does familial hypobetalipoproteinemia prevent the development of arterial atherosclerotic lesions?
This first documented autopsy study of a patient with familial hypobetalipoproteinemia revealed a complete absence of arterial atherosclerotic lesions, supporting the profound antiatherogenic effect of lifelong low LDL cholesterol.
Single autopsy without atherosclerosis in familial hypobetalipoproteinemia; hypothesis-generating for lifelong low LDL effects, does not change practice.
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Jessica A. Kahn (1978) studied this question.
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