Key result
An increase in right atrial sphericity index >0.24 measured by 3D echocardiography strongly predicted clinical deterioration in PAH patients over 1 year (sensitivity 96%, specificity 90%, AUC 0.97).
Why the study?
Does right atrial and ventricular remodelling assessed by 3DE predict clinical deterioration in patients with pulmonary arterial hypertension?
Population
62 consecutive patients with pulmonary arterial hypertension (PAH) and 30 healthy volunteers
Design
Cohort
Follow-up
1 year
Authors
Loading...
May aid PAH risk stratification via 3DE; leaves open prospective validation before clinical adoption.
Cohort (n=92)
Does right atrial and ventricular remodelling assessed by 3DE predict clinical deterioration in patients with pulmonary arterial hypertension?
Effect estimate: AUC 0.97
Real-time 3D echocardiographic measurement of right atrial sphericity index is a highly sensitive and specific predictor of clinical deterioration in patients with pulmonary arterial hypertension.
Grapsa et al. (2012) conducted a cohort in Pulmonary arterial hypertension (PAH) (n=92). Increase of right atrial sphericity index >0.24 vs. Increase of right atrial sphericity index ≤0.24 was evaluated on Clinical deterioration (increase of functional class or admission to the hospital due to right heart failure) (AUC 0.97). An increase in right atrial sphericity index >0.24 measured by 3D echocardiography strongly predicted clinical deterioration in PAH patients over 1 year (sensitivity 96%, specificity 90%, AUC 0.97).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: