A series of 17 monozygotic twins discordant for schizophrenia was studied intensively at the National Institute of Mental Health between 1963 and 1967. Sixteen pairs were interviewed a mean of 7.8 years after original admission. It was found that one pair is now concordant for schizophrenia, three previously healthy co-twins show new psychopathology of a possibly schizophrenic nature, and 12 twin pairs remain stably discordant.
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Robert H. Belmaker (1974) studied this question.
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