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Surfaces that respond to multiple stimuli may be well-suited for drug delivery applications. Here, such a surface is prepared by coating a silicon wafer with a block copolymer comprising a pH/glucose- and a temperature-sensitive block. The figure shows how the multiresponsive surfaces work in response to glucose concentration at pH 7. 4 and at a temperature of 26 °C. Under these conditions the surface shows a reversible change from superhydrophobic to superhydrophilic. Supporting information for this article is available on the WWW under http: //www. wiley-vch. de/contents/jc₂089/2007/c2334ₛ. pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Xia et al. (Wed,) studied this question.