Population
Human platelets in citrated plasma
Design
Preclinical
Authors
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Weak agonist synergies fail to mimic strong agonists in platelets; leaves open whether this refines thrombotic risk models and requires in vivo validation.
This in vitro study demonstrates that combinations of weak platelet agonists do not replicate the effects of strong agonists, and response patterns are driven by the agonist present at a higher relative concentration.
Huang et al. (1981) studied this question.
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