Population
Rats 3 to 4 weeks after myocardial infarction (MI)
Comparison
Myocardial infarction vs Sham-operated rats
Design
Preclinical
Follow-up
3 to 4 weeks
Authors
Loading...
Findings in rat models should not change post-MI arrhythmia care; leaves open human confirmation of Ito-mediated VT mechanisms.
Post-MI ventricular arrhythmias in rats are driven by prolonged action potential duration and repolarization heterogeneity due to decreased transient outward K+ currents.
Qin et al. (1996) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: