Why the study?
Does precordial T wave alternans analysis accurately track cardiac vulnerability to ventricular arrhythmias during acute myocardial ischaemia and reperfusion?
Population
61 chloralose anaesthetised dogs undergoing acute occlusion of the left anterior descending coronary artery…
Comparison
Precordial ECG monitoring and T wave alternans… vs Lead II or Frank leads
Design
Preclinical
Authors
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Precordial TWA monitoring merits prospective human validation during ischaemia; leaves open translation from canine models to clinical risk stratification.
Does precordial T wave alternans analysis accurately track cardiac vulnerability to ventricular arrhythmias during acute myocardial ischaemia and reperfusion?
Precordial T wave alternans analysis provides a non-invasive method to track cardiac vulnerability to ventricular arrhythmias during acute myocardial ischaemia and reperfusion.
Nearing et al. (1994) studied this question.
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