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January 1, 1965Japanese Heart JournalOpen Access

Origination and Transmission of Impulse in the Right Auricle

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Population

36 adult mongrel dogs (5 to 10 Kg) and 31 adult rabbits (2.0 to 2.9 Kg)

Comparison

Intracellular microelectrode mapping, artificial… vs Intact right atrial musculature

Design

Preclinical

Authors

KYKazuo YamadaMHMaretsugu HoribaYSYukio Sakaida

Discussion

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Overview

Does not support practice changes; leaves open translation of crista terminalis conduction to human electrophysiology.

Structured PICO

P
Population
36 adult mongrel dogs (5 to 10 Kg) and 31 adult rabbits (2.0 to 2.9 Kg)
I
Intervention
Intracellular microelectrode mapping, artificial driving, cutting of the crista terminalis, and injection of 2% osmic acid solution into the crista terminalis
C
Comparator
Intact right atrial musculature (measurements taken before cutting or osmic acid injection)
O
Outcome
Origination location of pacemaker potential and conduction rate/spread of activation in the right atriumsurrogate

This foundational preclinical study demonstrated that the crista terminalis serves as the primary rapid conduction pathway for electrical impulses traveling from the sinoatrial node to the atrioventricular node.

Cite This Study

Yamada et al. (1965) studied this question.

synapsesocial.com/papers/6a2285f5f4540fbb24541122https://doi.org/10.1536/ihj.6.71
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