Why the study?
The coronary adventitia and its vasa vasorum have attracted attention as an inflammatory source, motivating assessment of the link between local inflammation in adjacent epicardial adipose tissue and coronary atherosclerosis.
Is local inflammation in epicardial adipose tissue and adventitial vasa vasorum density associated with lipid-rich coronary plaques?
Is local inflammation in epicardial adipose tissue and adventitial vasa vasorum density associated with lipid-rich coronary plaques?
Lipid-rich coronary plaques are associated with increased adventitial vasa vasorum density and local inflammation in adjacent epicardial adipose tissue, suggesting a role for EAT inflammation in plaque progression.
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EAT inflammation associates with lipid-rich plaques; leaves open whether targeting vasa vasorum alters progression.
Ito et al. (2020) studied this question.
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