Key result
Depression and anxiety are significant independent risk factors for cardiovascular morbidity and mortality, and SSRIs are considered the first-line pharmacological treatment due to their cardiovascular safety profile.
This review highlights the biological correlations between depression, anxiety, and cardiovascular disease, emphasizing the cardiovascular safety profile of SSRIs compared to tricyclic antidepressants in this patient population.
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Torta et al. (2002) conducted a review in Depression, anxiety, and cardiovascular disease. Antidepressants (SSRIs, TCAs, NSRIs, NARIs, NaSSAs) was evaluated. Depression and anxiety are significant independent risk factors for cardiovascular morbidity and mortality, and SSRIs are considered the first-line pharmacological treatment due to their cardiovascular safety profile.
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