July 17, 2009Muscle & Nerve

Hereditary inclusion‐body myopathy: Clues on pathogenesis and possible therapy

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Population

Patients with hereditary inclusion-body myopathy (h-IBM) or distal myopathy with rimmed vacuoles (DMRV)

Design

Review

Authors

ABAldobrando BroccoliniUniversità Cattolica del Sacro Cuore TGTeresa GidaroSorbonne Université RMRoberta MorosettiAgostino Gemelli University Polyclinic

Discussion

Member takes

Implication

May guide recognition of GNE-related myopathy; leaves open validation of sialic acid pathway therapies in trials.

Structured PICO

Population

Patients with hereditary inclusion-body myopathy (h-IBM) or distal myopathy with rimmed vacuoles (DMRV)

This review summarizes the clinical features, pathogenic mechanisms involving GNE gene mutations, and therapeutic perspectives for hereditary inclusion-body myopathy.

Cite This Study

Broccolini et al. (2009) studied this question.

synapsesocial.com/papers/6a229b2ad5ef0a743714a6cc https://doi.org/10.1002/mus.21385

View Full Paper

Ask AI

Bookmark

Hereditary inclusion‐body myopathy: Clues on pathogenesis and possible therapy

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Hereditary inclusion‐body myopathy: Clues on pathogenesis and possible therapy

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider