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January 1, 1995GutOpen Access

Potential role of superantigen induced activation of cell mediated immune mechanisms in the pathogenesis of Crohn's disease.

J P Ibbotson John R. Lowes

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Potential role of superantigen

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Ibbotson et al. (1995) studied this question.

synapsesocial.com/papers/6a22a46965451dc9090e06ff https://doi.org/10.1136/gut.36.1.1

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Increased Circulating Ia-Antigen-Bearing T Cells in Type I Diabetes MellitusOriginal Research · 1982 · 222 citations
2In Vivo Activated T Lymphocytes in the Peripheral Blood and Cerebrospinal Fluid of Patients with Multiple SclerosisOriginal Research · 1985 · 304 citations
3Intestinal lymphocyte subpopulations in inflammatory bowel disease: an analysis by immunohistological and cell isolation techniques.Original Research · 1984 · 267 citations
4Peripheral blood and mesenteric lymph node lymphocytes in Crohn's disease.Original Research · 1980 · 9 citations
5Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells.Original Research · 1988 · 921 citations

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Activation of peripheral blood and intestinal lamina propria lymphocytes in Crohn's disease. In vivo state of activation and in vitro response to stimulation as defined by the expression of early activation antigens.1987
Differential expression of CD25 (interleukin-2 receptor) on lamina propria T cells and macrophages in the intestinal lesions in Crohn's disease and ulcerative colitis.1990
Spontaneous release of interferon gamma by intestinal lamina propria lymphocytes in Crohn's disease. Kinetics of in vitro response to interferon gamma inducers.1991

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