A 27-year-old diabetic man was admitted to the Toronto General Hospital in severe ketoacidosis after five days of nausea and vomiting.The patient had had diabetes mellitus for 15 years and had been admitted to the Toronto General Hospital on five previous occasions for control of his disease — once in ketoacidosis and once with severe hypoglycemia.Six days before the most recent admission, he had joint pains, followed by anorexia, nausea, and vomiting. He was unable to retain food or liquids and had decreased his insulin dose from 80 to 40 units in four divided doses daily. He became . . .
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Burrow et al. (1982) studied this question.