Key result
Echocardiography, enhanced by contrast agents and sequential imaging, serves as a practical and accessible tool for detecting and managing left ventricular thrombus after anterior myocardial infarction.
Why the study?
Left ventricular thrombus after anterior myocardial infarction carries high risk, and while cardiac magnetic resonance is the gold standard, it is costly, time-consuming, and not universally available.
Does echocardiographic-guided management improve detection and outcomes of left ventricular thrombus in patients with recent anterior myocardial infarction?
Does echocardiographic-guided management improve detection and outcomes of left ventricular thrombus in patients with recent anterior myocardial infarction?
Echocardiography, enhanced by contrast and sequential imaging, provides a practical and accessible alternative to CMR for detecting and managing left ventricular thrombus after anterior myocardial infarction.
May support echo as accessible LV thrombus screening post-anterior MI; leaves open randomized outcome trials versus CMR.
Despite advancement in therapy and management, left ventricular thrombus (LVT) after anterior myocardial infarction (MI) is sporadically encountered and remains associated with a very high risk of major cardiovascular events and mortality. Cardiac magnetic resonance (CMR) is considered the gold standard technique for LVT detection, but it is a time consuming and expensive test not available in all centers, especially when repeated exams are necessary. Transthoracic echocardiography represents a useful tool to screen for LVT and to identify predictors of high risk of developing LVT. The advances in ultrasound technology and the use of contrast agents may potentially help clinicians to identify LVT and the use of sequential echocardiography for each patient with acute MI complicated by LVT may provide an opportunity to quantify regression and its correlation with outcomes to tailor the management of these patients. Hence, this narrative review focuses on the added value of echocardiographic-guided LVT management in patients with recent anterior MI to reduce mortality and morbidity excess related to LVT based on current evidence.
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Barbieri et al. (2020) conducted a review in Left ventricular thrombus after anterior myocardial infarction. Echocardiography vs. Cardiac magnetic resonance was evaluated. Echocardiography, enhanced by contrast agents and sequential imaging, serves as a practical and accessible tool for detecting and managing left ventricular thrombus after anterior myocardial infarction.
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