Key result
Fetal and neonatal NT-proBNP levels were significantly lower in intrauterine-growth-restricted pregnancies compared with appropriate-for-gestational-age pregnancies (p ≤ 0.049).
Why the study?
Are NT-proBNP levels different between intrauterine-growth-restricted (IUGR) and appropriate-for-gestational-age (AGA) pregnancies?
Observational (n=80)
Are NT-proBNP levels different between intrauterine-growth-restricted (IUGR) and appropriate-for-gestational-age (AGA) pregnancies?
Answers are grounded in this paper and cite their sources.
Fetal and neonatal NT-proBNP levels are lower in IUGR compared with AGA pregnancies, peaking on day 1 postpartum.
OBJECTIVE: To investigate changes in NT-proBNP in intrauterine-growth-restricted (IUGR) and appropriate-for-gestational-age (AGA) pregnancies. METHODS: NT-proBNP levels were measured in 40 mothers (MS), umbilical cords (UC), and their 20 IUGR/ 20 AGA neonates on day 1 (N1) and day 4 (N4). RESULTS: UC, N1, and N4 NT-proBNP was lower in IUGR pregnancies (p <or= 0.049). In both groups, NT-proBNP levels were similar in MS and higher in N1 (p <or= 0.001). In AGA, MS NT-proBNP correlated positively with UC. CONCLUSIONS: Fetal and neonatal NT-proBNP levels are lower in IUGR compared with AGA, probably due to blood flow redistribution in IUGR and NT-proBNP placental transport in AGA. NT-proBNP levels peak on N1.
No takes yet. Share an insight, caveat, or question.
Iacovidou et al. (2007) conducted an observational in Intrauterine growth restriction (n=80). Intrauterine-growth-restricted (IUGR) pregnancy vs. Appropriate-for-gestational-age (AGA) pregnancy was evaluated on NT-proBNP levels in umbilical cords and neonates on day 1 and day 4 (p=≤0.049). Fetal and neonatal NT-proBNP levels were significantly lower in intrauterine-growth-restricted pregnancies compared with appropriate-for-gestational-age pregnancies (p ≤ 0.049).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: