Why the study?
BNP and NT-pro BNP reference intervals are undefined in pregnancy, leaving uncertainty regarding their interpretation when investigating suspected peripartum cardiomyopathy.
What are the trimester-specific reference intervals for BNP and NT-pro BNP in healthy pregnant women?
What are the trimester-specific reference intervals for BNP and NT-pro BNP in healthy pregnant women?
This study establishes trimester- and BMI-specific reference intervals for NT-pro BNP and BNP in healthy pregnant women, providing essential baseline data for investigating suspected peripartum cardiomyopathy.
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Defines trimester-specific BNP/NT-proBNP intervals; may aid peripartum cardiomyopathy evaluation but leaves validation and clinical adoption open.
Dockree et al. (2021) studied this question.
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