Key result
BNP >100 pg/ml predicts cardiac complications in pregnancy with high diagnostic accuracy.
Why the study?
Although natriuretic peptides are well-established diagnostic and risk markers in non-pregnant populations, their clinical usefulness in pregnancy and cardiovascular risk assessment is limited.
Does BNP and NT-proBNP testing accurately diagnose and predict cardiac complications in pregnant women?
Does BNP and NT-proBNP testing accurately diagnose and predict cardiac complications in pregnant women?
BNP and NT-proBNP are valuable markers for diagnosing and predicting cardiac complications in pregnancy, with a BNP >100 pg/ml showing high diagnostic accuracy.
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May aid cardiac risk assessment in pregnancy; leaves open need for prospective validation before routine use.
Quek et al. (2025) studied this question. A BNP level >100 pg/ml has high diagnostic accuracy (sensitivity 98%, specificity 92%) for predicting cardiac complications in pregnancy.
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