Key result
South Asian adults had significantly fewer retinal arteriolar vessels (10.8 vs 12.9, p<0.001) and bifurcations compared to age- and sex-matched European adults, indicating microcirculatory rarefaction.
Why the study?
Does South Asian ethnicity associate with differences in retinal microcirculation compared to European ethnicity in middle-aged adults?
Population
287 middle-aged adults matched for age and sex, recruited from the London Life Science Prospective…
Comparison
South Asian ethnicity vs European ethnicity
Design
Cross-sectional
Authors
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May indicate microcirculatory differences contributing to CV risk in South Asians; leaves open causal role and clinical utility pending longitudinal data.
Cross-Sectional (n=287)
Does South Asian ethnicity associate with differences in retinal microcirculation compared to European ethnicity in middle-aged adults?
Absolute Event Rate: 10.8% vs 12.9%
p-value: p=<0.001
South Asian adults exhibit significant rarefaction and elongation of the retinal microvasculature compared to Europeans, which may contribute to their elevated cardiovascular risk.
Hughes et al. (2013) conducted a cross-sectional in Cardiovascular Risk (n=287). South Asian ethnicity vs. European ethnicity was evaluated on Number of retinal arteriolar vessels (p=<0.001). South Asian adults had significantly fewer retinal arteriolar vessels (10.8 vs 12.9, p<0.001) and bifurcations compared to age- and sex-matched European adults, indicating microcirculatory rarefaction.
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