Why the study?
Are dependent and self-critical personality traits associated with life events, and do they change with fluoxetine treatment in depressed outpatients?
Observational (n=142)
Are dependent and self-critical personality traits associated with life events, and do they change with fluoxetine treatment in depressed outpatients?
Answers are grounded in this paper and cite their sources.
Fluoxetine treatment significantly improves dependent and self-critical personality traits as well as depression severity in depressed outpatients.
OBJECTIVE: To determine whether dependent and self-critical personality traits are associated with specific types of life events and whether these traits change with pharmacotherapy. METHOD: Overall, 142 depressed outpatients completing 8 weeks of fluoxetine treatment were administered the Life Experiences Survey (LES) at baseline and the Dysfunctional Attitude Scale (DAS) and Hamilton Depression Rating Scale (HDRS) at baseline and endpoint. RESULTS: The DAS dependency subscale, but not the self-criticism subscale, showed significant correlations with life events regardless of congruency. Baseline HDRS scores were positively correlated with both DAS subscales and total score. The DAS subscales, the total DAS score, and the HDRS all improved significantly with treatment. CONCLUSIONS: These results confirm a growing body of research that has found an association between sociotropic or dependent personality traits and life events.
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Zaretsky et al. (1997) conducted an observational in Major Depressive Disorder (n=142). Fluoxetine was evaluated on Correlation of dependent and self-critical personality traits with life events and change with pharmacotherapy.
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