Key result
Smoking acutely deteriorated aortic elastic properties, significantly increasing the slope of the pressure-diameter loop and decreasing aortic distensibility compared to sham smoking (P<0.001).
Why the study?
Does acute smoking deteriorate aortic elastic properties in male smokers undergoing cardiac catheterization?
RCT (n=40)
Randomly assigned
Does acute smoking deteriorate aortic elastic properties in male smokers undergoing cardiac catheterization?
p-value: p=<.001
Acute smoking significantly deteriorates aortic elastic properties, which may contribute to its adverse cardiovascular effects.
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Supports immediate smoking cessation counseling in cardiac patients; confirms acute vascular harm in an RCT.
Stefanadis et al. (1997) conducted an RCT in Chest pain evaluation in current and long-term smokers (n=40). Smoking vs. Sham smoking was evaluated on Aortic elastic properties (slope of the pressure-diameter loop and aortic distensibility) (p=<.001). Smoking acutely deteriorated aortic elastic properties, significantly increasing the slope of the pressure-diameter loop and decreasing aortic distensibility compared to sham smoking (P<0.001).
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