Key result
Malignant endothelial neoplasms of the serous membranes mimic mesothelioma but can be distinguished by strong vimentin expression, absent/low cytokeratin, and positivity for ≥2 endothelial markers.
Population
14 patients with epithelioid hemangioendothelioma or epithelioid angiosarcoma diffusely involving the…
Comparison
Histological and immunohistochemical analysis vs Control group of 39 mesotheliomas and >60…
Design
Case_series
Authors
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Consider endothelial markers in mesothelioma mimics; case reports leave diagnostic criteria open to validation.
Observational (n=113)
Epithelioid hemangioendothelioma and epithelioid angiosarcoma can mimic mesothelioma but can be distinguished by strong vimentin expression and coexpression of endothelial markers.
Lin et al. (1996) conducted an observational in Malignant vascular tumors of the serous membranes mimicking mesothelioma (n=113). Epithelioid hemangioendothelioma or epithelioid angiosarcoma vs. Mesothelioma and adenocarcinoma was evaluated on Immunohistochemical marker expression. Malignant endothelial neoplasms of the serous membranes mimic mesothelioma but can be distinguished by strong vimentin expression, absent/low cytokeratin, and positivity for ≥2 endothelial markers.
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