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May inform exploratory genomic use in cardiology; leaves open prospective validation before practice change.
Recent technological advances in gene analysis have provided the modern day cardiologist additional tools to diagnose and risk stratify the cardiovascular patient. This provides a potential window to prevent disease and to maintain wellness, with personalised intervention, in contrast to the traditional approach of treatment to ailment. Many genetic variations predisposing to various cardiovascular pathologies have been described. In some cases the pathological pathways involved are evident, whereas in most heterogeneous conditions the mechanisms remain unresolved. Translational research is progressing in such a rapid pace it is highly likely that coming years will provide the clinical cardiologist many pathways of action for early diagnosis and for targeted treatment. We will review what genomic tools are currently available for the cardiologist to use in routine clinical practice.
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Prasad Gunaruwan (2014) studied this question.
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