Key result
Obesity in adolescents was associated with significantly higher serum NT-proBNP levels (76.0 pg/ml in severe obesity vs 44.3 pg/ml in controls) and correlated with early cardiovascular risk factors.
Why the study?
Are serum NT-proBNP levels associated with early cardiovascular risk factors and subclinical echocardiographic abnormalities in obese adolescents compared to healthy controls?
Cross-Sectional (n=201)
Single-blind
No
Are serum NT-proBNP levels associated with early cardiovascular risk factors and subclinical echocardiographic abnormalities in obese adolescents compared to healthy controls?
Absolute Event Rate: 76% vs 44.3%
p-value: p=0.002
May flag early cardiac strain in obese adolescents but should not change practice; leaves open prognostic value in prospective cohorts.
This study aimed to evaluate the associations between the N-Terminal pro B-type Natriuretic Peptide (NT-proBNP) levels and the metabolic, echocardiographic parameters, carotid Intima-Media Thickness (IMT) and Epicardial Adipose Tissue Thickness (EATT) in adolescent obesity.
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Özgür Pirgon (2015) conducted a cross-sectional in Adolescent obesity (n=201). Obesity vs. Healthy non-obese adolescents was evaluated on Serum NT-proBNP levels (pg/ml) (p=0.002). Obesity in adolescents was associated with significantly higher serum NT-proBNP levels (76.0 pg/ml in severe obesity vs 44.3 pg/ml in controls) and correlated with early cardiovascular risk factors.
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