Key result
A 33-year-old female with primary mediastinal large B-cell lymphoma exhibiting rare endobronchial involvement was successfully diagnosed via bronchoscopy and achieved a partial tumor response with R-CHASE chemotherapy.
Case Report (n=1)
This case report demonstrates that primary mediastinal large B-cell lymphoma can rarely present with endobronchial involvement, which can be successfully diagnosed via bronchoscopy and treated with R-CHASE chemotherapy.
Primary mediastinal large B-cell lymphoma (PMLBCL) is one of the subtypes of diffuse large B-cell lymphoma. We experienced a rare case of PMLBCL that exhibited endobronchial involvement. A 33-year-old Japanese female with the chief complaints of epigastralgia, back pain, and nausea visited a primary care hospital. Computed tomography of the chest and abdomen demonstrated a bulky mass in the left anterior mediastinum, multiple pulmonary nodules, axillary lymph node swelling, and a pancreatic tumor. Fiberoptic bronchoscopy showed a white-tinged irregularly shaped endobronchial tumor accompanied by capillary vessel dilation in the left upper lobar bronchus. Taken together, these findings resulted in a diagnosis of PMLBCL.
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Shimada et al. (2016) conducted a case report in Primary mediastinal large B-cell lymphoma (PMLBCL) (n=1). R-CHASE chemotherapy was evaluated on Tumor response. A 33-year-old female with primary mediastinal large B-cell lymphoma exhibiting rare endobronchial involvement was successfully diagnosed via bronchoscopy and achieved a partial tumor response with R-CHASE chemotherapy.
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