Why the study?
Pulmonary MALT lymphoma with isolated endobronchial manifestation has seldomly been reported, and differentiating pulmonary MALT lymphoma from other lung diseases is critical for management and treatment.
Primary pulmonary MALT lymphoma can rarely present with isolated endobronchial involvement and can be successfully managed with rituximab.
Rituximab may be an option for rare endobronchial pulmonary MALT lymphoma; leaves open need for confirmatory studies.
Primary pulmonary lymphoma is an uncommon disease, and extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) is the most common type of pulmonary lymphoma. The most frequent pattern observed in chest computed tomography (CT) is consolidation, followed by nodules and mass. The differentiation of pulmonary MALT lymphoma from other lung diseases is critical for disease management and treatment. However, pulmonary MALT lymphoma with isolated endobronchial manifestation has seldomly been reported. Here, we report a case of an elderly woman who presented with a four-month history of cough, dyspnoea, and haemoptysis. Chest CT scan revealed left main bronchus narrowing without lung parenchymal lesion. Bronchoscopic examination was performed, and the diagnosis of primary pulmonary MALT lymphoma with isolated endobronchial involvement was made. She has been successfully treated with rituximab.
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Liao et al. (2020) studied this question.
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