Key result
Alcoholics with cardiac vagal neuropathy exhibited larger resting pupillary diameters and greater pupil responses to methacholine than controls or alcoholics without vagal neuropathy.
Why the study?
Do alcoholics with cardiac vagal neuropathy have altered pupillary parasympathetic responses compared to controls and alcoholics without vagal neuropathy?
Population
30 alcoholics (12 with cardiac vagal neuropathy) and an unspecified number of control subjects
Comparison
Measurement of resting pupillary diameter and… vs Control subjects and alcoholics without vagal…
Design
Cross-sectional
Authors
Loading...
Supports systemic parasympathetic denervation in alcoholics with vagal neuropathy; leaves open whether pupillary testing aids diagnosis or prognosis.
Observational (n=30)
Do alcoholics with cardiac vagal neuropathy have altered pupillary parasympathetic responses compared to controls and alcoholics without vagal neuropathy?
Alcoholics with cardiac vagal neuropathy exhibit signs of parasympathetic denervation of the iris, suggesting systemic parasympathetic autonomic neuropathy.
Tan et al. (1984) conducted an observational in Alcoholism (n=30). Cardiac vagal neuropathy vs. Control subjects or alcoholics without vagal neuropathy was evaluated on Resting pupillary diameters and pupil responses to methacholine. Alcoholics with cardiac vagal neuropathy exhibited larger resting pupillary diameters and greater pupil responses to methacholine than controls or alcoholics without vagal neuropathy.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: