January 1, 1975Brain
The Sympathetic Nervous System in Alcoholic Neuropathy
Why the study?
What is the status of the sympathetic nervous system and baroreceptor function in patients with alcoholic neuropathy?
Population
12 subjects with alcoholic neuropathy undergoing clinical tests, and 4 alcoholic subjects undergoing autopsy
Comparison
Tests of autonomic function and quantitative… vs Control range
Design
Cross-sectional
Authors
Discussion
Loading...
Member takes
Implication
Supports baroreflex sparing despite sudomotor and Valsalva abnormalities in alcoholic neuropathy; hypothesis-generating for selective autonomic involvement.
Structured PICO
What is the status of the sympathetic nervous system and baroreceptor function in patients with alcoholic neuropathy?
P
Population
12 subjects with alcoholic neuropathy undergoing clinical tests, and 4 alcoholic subjects undergoing autopsy
I
Intervention
Tests of autonomic function and quantitative histological studies of greater splanchnic nerves
C
Comparator
Control range
O
Outcome
Autonomic function (sweat patterns, Valsalva ratio, postural hypotension, denervation hypersensitivity, baroreceptor function) and splanchnic nerve histologysurrogate
In alcoholic neuropathy, significant disturbances of blood pressure control are absent, correlating with preserved histology in the greater splanchnic nerve, despite abnormalities in sweating and Valsalva responses.
Cite This Study
Low et al. (1975) studied this question.