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December 1, 1987Postgraduate Medical JournalOpen Access

Autonomic neuropathy in an alcoholic population

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Why the study?

Does alcoholism increase the prevalence of autonomic neuropathy compared to age-sex matched controls?

Population

60 subjects total: 30 alcoholic subjects and 30 age-sex matched controls.

Comparison

Alcoholism (exposure) vs Age-sex matched controls

Design

Case-control

Authors

FBF.C. BarterSouthampton General HospitalATA.R. TannerRoyal Brisbane and Women's Hospital

Discussion

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Implication

Autonomic neuropathy may warrant evaluation in alcoholics despite absent symptoms; leaves open prognostic impact and need for prospective studies.

Structured PICO

Does alcoholism increase the prevalence of autonomic neuropathy compared to age-sex matched controls?

P
Population
60 subjects total: 30 alcoholic subjects and 30 age-sex matched controls.
I
Intervention
Alcoholism (exposure)
C
Comparator
Age-sex matched controls
O
Outcome
Autonomic nervous system integrity (presence of parasympathetic and/or sympathetic neuropathy) assessed via five simple tests of cardiovascular responsessurrogate

Alcoholic subjects have a notably higher prevalence of autonomic neuropathy compared to healthy controls, which is poorly predicted by symptoms and associated with older age, female sex, and established liver disease.

Cite This Study

Barter et al. (1987) studied this question.

synapsesocial.com/papers/6a8a77451acf8e321fbd7fdbhttps://doi.org/10.1136/pgmj.63.746.1033
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Natural History of Diabetic Autonomic Neuropathy1980 · 746 citations
  2. 2Role of vagal neuropathy in the hyponatraemia of alcoholic cirrhosis.1986 · 30 citations
  3. 3Diagnosis and management of diabetic autonomic neuropathy.1982 · 1,236 citations
  4. 4The Vagus and Sympathetic Nerves in Alcoholic Polyneuropathy1974 · 107 citations