Hemodialysis acutely increased right brachial-ankle pulse wave velocity from 1801 to 1946 cm/s (p<0.001), which returned to pre-dialysis levels on the next dialysis-free day, while ankle-brachial index remained constant.
Observational (n=89)
Yes
Does the timing of measurement relative to hemodialysis affect brachial-ankle pulse wave velocity and ankle-brachial index in hemodialysis patients?
When evaluating arterial stiffness using baPWV in hemodialysis patients, the measurement time relative to the dialysis session is essential as baPWV transiently increases after dialysis, whereas ABI remains constant and can be measured at any time.
Absolute Event Rate: 1946% vs 1801%
p-value: p=<0.001
In order to ensure that they are reliable markers of atherosclerosis and suitable for repetitive follow-up of disease progression and management responses in hemodialysis (HD) patients, brachial-ankle pulse wave velocity (baPWV) and ankle-brachial index (ABI) should be tested to see whether they change with different measurement time points. The aim of this study was to assess whether baPWV and ABI vary according to whether they are measured before HD, after HD, or on the next dialysis-free day. Eighty-nine patients undergoing regular HD were enrolled. The baPWV and ABI were measured 10-30 min before and after HD, and if patients agreed, on the next dialysis-free day. The third measurement of baPWV and ABI, performed 22+/-2 h after HD, was taken in 72 patients (81%). The body weight reduction after HD was 2.5+/-0.9 kg (por=0.498). In conclusion, despite the significant decrease in body weight and blood pressures, baPWV increased significantly after HD. In addition, baPWV, but not ABI, may vary at different measurement time points. Therefore, baPWV, but not ABI, should be assessed in a timely manner in HD patients.
Su et al. (2007) conducted an observational in End-stage renal disease on hemodialysis (n=89). Hemodialysis vs. Pre-hemodialysis baseline was evaluated on Right brachial-ankle pulse wave velocity (baPWV) in cm/s (p=<0.001). Hemodialysis acutely increased right brachial-ankle pulse wave velocity from 1801 to 1946 cm/s (p<0.001), which returned to pre-dialysis levels on the next dialysis-free day, while ankle-brachial index remained constant.