Key result
Metabolic syndrome was significantly associated with an increased risk of elevated brachial-ankle pulse wave velocity (OR 5.08) compared to having a normal waist circumference and no risk factors.
Why the study?
Does metabolic syndrome increase brachial-ankle pulse wave velocity in a Japanese population?
Population
525 men and women aged 30-79 years without a history of cardiovascular disease or cancer, and an…
Comparison
Presence of metabolic syndrome. vs Absence of metabolic syndrome.
Design
Cross-sectional
Authors
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Metabolic syndrome may flag elevated arterial stiffness risk; leaves open causal effects and need for longitudinal trials.
Cross-Sectional (n=525)
No
Does metabolic syndrome increase brachial-ankle pulse wave velocity in a Japanese population?
Odds Ratio: 5.08 (95% CI 2.16–11.9)
p-value: p=<0.001
Metabolic syndrome, as defined by Japanese guidelines, is significantly associated with increased arterial stiffness measured by brachial-ankle pulse wave velocity, driven largely by insulin resistance and blood pressure.
Tsubakimoto et al. (2006) conducted a cross-sectional in Metabolic syndrome and arterial stiffness (n=525). Metabolic syndrome vs. Normal waist circumference and 0 metabolic risk factors was evaluated on Elevated brachial-ankle pulse wave velocity (highest quartile) (OR 5.08, 95% CI 2.16-11.9, p=<0.001). Metabolic syndrome was significantly associated with an increased risk of elevated brachial-ankle pulse wave velocity (OR 5.08) compared to having a normal waist circumference and no risk factors.
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