Key result
A child with acute lymphoblastic leukemia in remission presented with pulmonary involvement as an unusual initial manifestation of Hodgkin's disease as a second malignancy.
Case Report (n=1)
Highlights an unusual presentation of Hodgkin's disease as a second malignancy in a child with acute lymphoblastic leukemia.
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Pulmonary Hodgkin’s as second malignancy after ALL warrants vigilance for atypical features in survivors; leaves open therapy-related effects on presentation.
Hodgkin's disease as a second malignancy in childhood acute lymphoblastic leukemia is of rare occurrence, with the first such case having only recently been described. The therapy for acute lymphoblastic leukemia may alter the pattern of presentation of Hodgkin's disease and its histology, making diagnosis difficult. In this report we discuss the clinical, histologic, and ultrastructural findings of a child with acute lymphoblastic leukemia in remission who had pulmonary involvement as an unusual initial presentation of Hodgkin's disease.
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Labotka et al. (1983) conducted a case report in Acute lymphoblastic leukemia and Hodgkin's disease (n=1). Therapy for acute lymphoblastic leukemia was evaluated on Clinical, histologic, and ultrastructural findings. A child with acute lymphoblastic leukemia in remission presented with pulmonary involvement as an unusual initial manifestation of Hodgkin's disease as a second malignancy.
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