Key result
Nicorandil successfully abolished intraoperative Torsade de Pointes in a single patient case.
Why the study?
Does nicorandil abolish intraoperative Torsade de Pointes?
Case Report (n=1)
Does nicorandil abolish intraoperative Torsade de Pointes?
Nicorandil may be an effective treatment for abolishing intraoperative Torsade de Pointes.
Hypothesis-generating for nicorandil in intraoperative TdP; should not change practice pending controlled data.
Torsade de Pointes (TdP), polymorphic ventricular tachycardia with QT interval prolongation, is one of the life-threatening arrhythmias and may occur in association with intracranial. 1-6 Nicorandil, a potassium-channel opener, has been used as a coronary vasodilator. 7 Recently antiarrhythmic therapy using nicorandil has been attempted. Chinushi et al. 8 reported that nicorandil suppressed TdP in patients with idiopathic long QT syndrome. We experienced a case in which TdP occurred during surgery and was clearly abolished by nicorandil
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Saitoh et al. (1998) conducted a case report in Intraoperative Torsade de Pointes (n=1). Nicorandil was evaluated on Abolishment of Torsade de Pointes. Nicorandil successfully abolished intraoperative Torsade de Pointes in a single patient case.
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