Key result
The transient dilatation index on Tc-99m tetrofosmin SPECT was significantly higher in patients with more occluded coronary arteries (P<0.01), detecting multi-vessel disease with 91.4% sensitivity.
Why the study?
Does the transient dilatation index (TDI) measured by exercise Tc-99m tetrofosmin myocardial SPECT accurately detect multiple-vessel coronary artery disease?
Cross-Sectional (n=75)
Does the transient dilatation index (TDI) measured by exercise Tc-99m tetrofosmin myocardial SPECT accurately detect multiple-vessel coronary artery disease?
p-value: p=<0.01
Transient left ventricular dilatation on Tc-99m tetrofosmin SPECT is a useful non-invasive marker for identifying patients with multi-vessel coronary artery disease.
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May aid non-invasive multi-vessel CAD detection on tetrofosmin SPECT; leaves open prospective validation before practice change.
Kinoshita et al. (2002) conducted a cross-sectional in Coronary artery disease (n=75). Transient dilatation index (TDI) on Tc-99m tetrofosmin myocardial SPECT vs. Controls and single-vessel disease was evaluated on Detection of two-vessel or three-vessel disease (p=<0.01). The transient dilatation index on Tc-99m tetrofosmin SPECT was significantly higher in patients with more occluded coronary arteries (P<0.01), detecting multi-vessel disease with 91.4% sensitivity.
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