Population
Actin, myosin, and heavy meromyosin in solution (in vitro biochemical assay)
Comparison
Addition of Mg++ ion and adenosine triphosphate… vs Noninteracting mixture of actin and myosin…
Design
Preclinical
Authors
Loading...
These in vitro distinctions remain preclinical; leaves open whether stable actomyosin complexes influence sarcomere function or therapeutic myosin targeting.
This basic science study demonstrates distinct biophysical differences in how actin interacts with intact myosin versus heavy meromyosin during ATP hydrolysis.
Eisenberg et al. (1967) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: