Newly Recognized Components of the Renin-Angiotensin System: Potential Roles in Cardiovascular and Renal Regulation
Key result
Recent advances in the understanding of the renin-angiotensin system, including local tissue RASs, renin receptor, ACE2, and ANG (1-7), highlight their roles in cardiovascular and renal regulation.
Design
Review
Authors
Discussion
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Implication
Extends RAS paradigm beyond canonical axis; leaves open whether ACE2/ANG(1-7) pathways warrant new therapeutic trials.
PICO
P
Population
Cardiovascular and renal regulation
I
Intervention / Comparator
Renin-angiotensin system components
This review highlights newly recognized components of the renin-angiotensin system and their potential roles in cardiovascular and renal regulation.
Cite This Study
Carey et al. (2003) conducted a review in Cardiovascular and renal regulation. Renin-angiotensin system components was evaluated. Recent advances in the understanding of the renin-angiotensin system, including local tissue RASs, renin receptor, ACE2, and ANG (1-7), highlight their roles in cardiovascular and renal regulation.