Key result
Abnormal baroreflex function, indicated by decreased heart rate variability, was associated with significantly higher blood pressure variability in hypertensive patients (0.018 vs 0.014, P < 0.001).
Cross-Sectional (n=111)
No
Baroreflex dysfunction, as indicated by abnormal heart rate variability, is associated with increased blood pressure variability in hypertensive patients, particularly in older individuals.
Supports baroreflex-BP variability link in hypertension; hypothesis-generating, should not change practice.
Objective: The aim of this study was to assess the relationship of blood pressure variability (BPV) and heart rate variability (HRV) to investigate the effect of baroreflex function on blood pressure variability. Methods: This study consisted of 111 subjects, including 32 normotensives and 79 hypertensives. All the subjects were given two concurrent tests: 24-hour Holter ECG and ambulatory blood pressure monitoring. According to standard deviation of normal-to-normal sinus RR intervals (SDNN) derived from the Holter ECG, the hypertensives were divided into two groups: an HRV normal group with SDNN > 100 ms and an HRV abnormal group with SDNN
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Wei et al. (2013) conducted a cross-sectional in Hypertension (n=111). Abnormal heart rate variability (SDNN < 100 ms) vs. Normal heart rate variability (SDNN > 100 ms) was evaluated on Blood pressure variability (BPV) (p=<0.001). Abnormal baroreflex function, indicated by decreased heart rate variability, was associated with significantly higher blood pressure variability in hypertensive patients (0.018 vs 0.014, P < 0.001).
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