What question did this study set out to answer?

To investigate the relationship between oral contraceptives, pregnancy, and endogenous hormone levels in gall stone disease among women.

June 16, 1984BMJOpen Access

Oral contraceptives, pregnancy, and endogenous oestrogen in gall stone disease--a case-control study.

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To investigate the relationship between oral contraceptives, pregnancy, and endogenous hormone levels in gall stone disease among women.
Case-control study involving 200 women with gall stone disease and 182 matched controls from the community.
Assessment of reproductive history and hormonal concentrations, particularly oestrone and pregnanediol.
Comparison of risks associated with contraceptive use and reproductive factors.
Young women using oral contraceptives showed increased gall stone disease risk, while older women had decreased risk.
Increasing parity was strongly associated with an elevated risk of gall stones, particularly in younger women.
Postmenopausal patients had significantly higher mean urinary oestrone levels than controls (p < 0.05).

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Implication

Case-control study examines the relationship between contraceptive use and gall stone disease risk in women, indicating varied susceptibility based on age and reproductive history.

Cite This Study

Scragg et al. (1984) studied this question.

synapsesocial.com/papers/6a2306305bf42efd08cb29a6 https://doi.org/10.1136/bmj.288.6433.1795

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Implication

Case-control study examines the relationship between contraceptive use and gall stone disease risk in women, indicating varied susceptibility based on age and reproductive history.

Oral contraceptives, pregnancy, and endogenous oestrogen in gall stone disease--a case-control study.

Key Points

Discussion

Implication

Cite This Study

Oral contraceptives, pregnancy, and endogenous oestrogen in gall stone disease--a case-control study.

Key Points

Discussion

Implication

Cite This Study

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