Key result
Transcatheter ASD occlusion in a patient with factor XII deficiency resulted in thrombus formation on the device and acute stroke despite heparin anticoagulation.
Population
1 patient with coagulation factor XII deficiency undergoing transcatheter occlusion of an atrial septal defect
Design
Case_report
Follow-up
weeks
Authors
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Factor XII deficiency may heighten thromboembolic risk after ASD occlusion; leaves open tailored anticoagulation protocols for prospective study.
Case Report (n=1)
Patients with factor XII deficiency are at risk for thromboembolism after ASD occlusion, highlighting the need for pre-procedural coagulation screening and post-procedural TEE monitoring.
Gastmann et al. (1998) conducted a case report in Atrial septal defect and coagulation factor XII deficiency (n=1). Transcatheter occlusion of atrial septal defect was evaluated on Thrombus formation and acute stroke. Transcatheter ASD occlusion in a patient with factor XII deficiency resulted in thrombus formation on the device and acute stroke despite heparin anticoagulation.
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