Changes in Cardiac Autonomic Nervous Activity During Menstrual Cycle of Young Women

The purpose of this study was to evaluate the function of cardiac autonomic nervous activity and post-exercise vagal reaction during the menstrual cycle. The subjects were healthy young women (n=13, age 19.9±0.6 years) with normal menstrual cycles. Power spectral analysis of heart rate variability was used to examine cardiac autonomic nervous activity. In addition, the time con stant of heart rate decline for the first 30 sec (T30) after exercise was used to examine post-exercise vagal reactivation.Results show that the cardiac autonomic nervous activity changes during the menstrual cycle. Also, T30 shows significant change during the menstrual cycle, especially T30 retardation in the early luteal phase. These results suggest that an imbalance of estradiol and progesterone hormones may be responsible for these changes in cardiac autonomic nervous activity during the menstrual cycle.