What does this research mean for the field?

The widely cited meta-analytic estimate that suicide risk is 100-fold higher in people living with HIV compared to the general population is questionable and requires critical reappraisal. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.CHALLENGES_CONSENSUS.

August 1, 2025General Psychiatry3 citationsOpen Access

Is suicide risk 100‐fold higher in people with HIV? A critical appraisal of a meta‐analysis

AHAndreas D. HaasUniversity of Bern YRYann RuffieuxUniversity of Bern MTMpho TlaliUniversity of Cape Town

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Abstract

To the editor: “A recent systematic review shows that the risk of death by suicide is 100 times higher in people living with HIV than in the general population”—World Health Organization, 2022The estimate that the risk of suicide is 100-fold higher in people with HIV (PWH) than in the general population is widely cited, including in the World Health Organization’s (WHO’s) World Mental Health report from which the above quote is taken.

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