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March 12, 2020Health and Quality of Life OutcomesOpen Access

The associations between psychological distress and health-related quality of life in patients with non-cardiac chest pain

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Key result

Patients with non-cardiac chest pain and a history of cardiac disease reported significantly lower health-related quality of life (EQ-5D index 0.6 vs 0.7) compared to those without a history of cardiac disease.

Why the study?

There was a lack of knowledge on how a history of cardiac disease influences the association between psychological wellbeing and health-related quality of life in patients with non-cardiac chest pain.

Does psychological distress associate with health-related quality of life in patients with non-cardiac chest pain?

Population

Five hundred fifty-two patients discharged with NCCP from four hospitals in Southeast Sweden

Comparison

Patients with NCCP with vs without a history of CD

Design

Multicenter cross-sectional study

Authors

GMGhassan MouradJAJenny AlwinTJTiny Jaarsma

Discussion

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Overview

Cardiac history may flag non-cardiac chest pain patients for psychological assessment; cross-sectional data leave causal links and interventions open.

Study Design

Type

Cross-Sectional (n=552)

Multicenter

Yes

Structured PICO

Does psychological distress associate with health-related quality of life in patients with non-cardiac chest pain?

P
Population
552 adults aged 18 and older discharged with non-cardiac chest pain from four hospitals in Sweden, evaluated for health-related quality of life and psychological distress.
O
Outcome
Health-related quality of life (HRQoL) measured by EQ-5D-5L and EQ-VAS, and its association with psychological distress (cardiac anxiety, depressive symptoms, fear of body sensations, and somatization)patient reported

Main Result

Absolute Event Rate: 0.6% vs 0.7%

p-value: p=<0.001

Patients with non-cardiac chest pain, particularly those with a history of cardiac disease, experience poor health-related quality of life which is significantly associated with psychological distress.

Limitations

  • No access to medical charts, leading to reliance on few inclusion criteria
  • Low response rate
  • Potential selection bias due to differences in demographical profile between responders and non-responders
  • No access to medical charts, relying on few inclusion criteria
  • Differences in demographical profile between responders and non-responders (younger patients did not respond, older patients declined participation)

Cite This Study

Mourad et al. (2020) conducted a cross-sectional in Non-cardiac chest pain (n=552). History of cardiac disease vs. No history of cardiac disease was evaluated on EQ-5D index (p=<0.001). Patients with non-cardiac chest pain and a history of cardiac disease reported significantly lower health-related quality of life (EQ-5D index 0.6 vs 0.7) compared to those without a history of cardiac disease.

synapsesocial.com/papers/6a2314ea3c6dd25ddfc44989https://doi.org/10.1186/s12955-020-01297-0
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