Why the study?
Does chelation therapy with intravenous injections of edetate disodium improve clinical efficacy and safety in patients with coronary or other arterial atherosclerosis?
Population
Patients with coronary or other arterial atherosclerosis
Design
Review
Authors
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Insufficient evidence advises against chelation for atherosclerosis; leaves open whether rigorous RCTs could identify benefit.
Does chelation therapy with intravenous injections of edetate disodium improve clinical efficacy and safety in patients with coronary or other arterial atherosclerosis?
There is currently a lack of acceptable evidence to support the use of chelation therapy for the treatment of atherosclerotic vascular disease.
Rathmann et al. (1984) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: