Key result
Ischemia during exercise echocardiography in asymptomatic patients after coronary revascularization was associated with increased cardiac mortality (HR 2.10; 95% CI 1.05-4.19; P=.04).
Why the study?
Does exercise echocardiography predict cardiac mortality and identify patients who benefit from repeated revascularization in asymptomatic patients after previous coronary revascularization?
Population
2105 asymptomatic patients with previous coronary revascularization, mean age 64 years, 15% women, 40% with…
Design
Cohort
Follow-up
mean 5.7 years
Authors
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Should not yet prompt routine testing or reintervention in asymptomatic patients; leaves open whether detected ischemia warrants targeted trials.
Cohort (n=2,105)
Does exercise echocardiography predict cardiac mortality and identify patients who benefit from repeated revascularization in asymptomatic patients after previous coronary revascularization?
Hazard Ratio: 2.1 (95% CI 1.05–4.19)
p-value: p=.04
Routine exercise echocardiography in asymptomatic patients after revascularization identifies ischemia associated with higher mortality, but subsequent revascularization does not appear to improve outcomes, questioning the clinical utility of such testing.
Harb et al. (2012) conducted a cohort in Asymptomatic after coronary revascularization (n=2,105). Ischemia during exercise echocardiography vs. No ischemia was evaluated on Cardiac mortality (HR 2.10, 95% CI 1.05-4.19, p=.04). Ischemia during exercise echocardiography in asymptomatic patients after coronary revascularization was associated with increased cardiac mortality (HR 2.10; 95% CI 1.05-4.19; P=.04).
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