Key result
Hypoxia significantly reduced physical performance (P≤0.004) and voluntary activation (P=0.039), whereas mental fatigue had no effect on physical or cognitive performance (P≥0.138).
Why the study?
The individual and combined effects of mental fatigue and hypoxia on physical and cognitive performance were not fully established.
Does mental fatigue combined with hypoxia impact physical or cognitive performance in healthy males?
Does mental fatigue combined with hypoxia impact physical or cognitive performance in healthy males?
p-value: p=≤0.004
Hypoxia impairs physical performance, but mental fatigue does not independently affect self-paced physical or cognitive performance.
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Hypoxia impairs performance via reduced voluntary activation; hypothesis-generating for mental fatigue interactions under combined stressors.
O’Keeffe et al. (2021) studied this question. Mental fatigue and hypoxia vs. Normoxia (0.209 FiO2) and no mental fatigue was evaluated on Physical performance (average power output, oxygen consumption, muscle oxygenation) and cognitive performance (p=≤0.004). Hypoxia significantly reduced physical performance (P≤0.004) and voluntary activation (P=0.039), whereas mental fatigue had no effect on physical or cognitive performance (P≥0.138).
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