Key result
Coronary artery bypass grafting causes a significant reduction in heart rate variability that recovers within six months and is not considered relevant in predicting mortality.
Why the study?
Does reduced heart rate variability after coronary artery bypass grafting predict mortality?
Does reduced heart rate variability after coronary artery bypass grafting predict mortality?
Reduced heart rate variability after CABG is a common, transient physiological response that, unlike post-MI HRV reduction, does not carry prognostic relevance for mortality.
Post-CABG HRV reduction warrants no mortality risk stratification; leaves open prospective validation versus post-MI contexts.
Heart rate variability is a physiological feature indicating the influence of the autonomic nervous system on the heart rate. Association of the reduced heart rate variability due to myocardial infarction and the increased postinfarction mortality was first described more than thirty years ago. Many studies have unequivocally demonstrated that coronary artery bypass grafting surgery generally leads to significant reduction in heart rate variability, which is even more pronounced than after myocardial infarction. Pathophysiologically, however, the mechanisms of heart rate variability reduction associated with acute myocardial infarction and coronary artery bypass grafting are different. Generally, heart rate variability gradually recovers to the preoperative values within six months of the procedure. Unlike the reduced heart rate variability in patients having sustained myocardial infarction, a finding of reduced heart rate variability after coronary artery bypass surgery is not considered relevant in predicting mortality. Current knowledge about changes in heart rate variability in coronary patients and clinical relevance of such a finding in patients undergoing coronary artery bypass grafting are presented.
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Lakušić et al. (2015) conducted a review in Coronary artery disease undergoing coronary artery bypass grafting. Coronary artery bypass grafting vs. Myocardial infarction was evaluated on Heart rate variability reduction and mortality prediction. Coronary artery bypass grafting causes a significant reduction in heart rate variability that recovers within six months and is not considered relevant in predicting mortality.
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