Key result
Activation of the endothelin system emerges as an important pathway causing the clinical manifestations of pre-eclampsia, including hypertension and proteinuria.
Endothelin-1 activation emerges as a critical pathway in pre-eclampsia pathogenesis, highlighting endothelin receptor blockers as a potential therapeutic strategy.
No takes yet. Share an insight, caveat, or question.
Endothelin pathway activation may identify a novel target in pre-eclampsia; leaves open whether receptor blockade improves outcomes in prospective trials.
Saleh et al. (2016) conducted a review in Pre-eclampsia. Endothelin-1 was evaluated. Activation of the endothelin system emerges as an important pathway causing the clinical manifestations of pre-eclampsia, including hypertension and proteinuria.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: