Key result
Patients who experienced syncope during head-up tilt testing had a significantly higher mean number of previous syncopal events (6.3 vs 2.4, p<0.001) and more frequently reported prodromal symptoms compared to asymptomatic patients.
Why the study?
Do clinical history and physical characteristics predict the success of head-up tilt table testing at diagnosing syncope in patients with suspected neurocardiogenic syncope?
Cross-Sectional (n=100)
Do clinical history and physical characteristics predict the success of head-up tilt table testing at diagnosing syncope in patients with suspected neurocardiogenic syncope?
Frequency of prior syncope, specific prodromal symptoms, and increased body height can help predict a positive head-up tilt table test in patients with suspected syncope.
BACKGROUND: Syncope is a relevant health problem in military environments. Reliable diagnosis is challenging. Tilt table testing is an important tool for syncope diagnosis. The aim of this study was to determine whether signs such as prodromal symptoms, co-morbidity, frequency of syncopal events, body length, body mass index, and electrocardiography abnormalities can be used to predict the success of tilt table testing at diagnosing syncope. METHODS: Data from 100 patients with histories of syncope or pre-syncope, who were diagnosed using head-up tilt table testing, were retrospectively analyzed in a cross-sectional analysis. The diagnostic procedure was based upon a modified version of the Westminster protocol without any pharmacological provocation. RESULTS: Patients showing pathological reaction patterns during tilt table testing suffered from prodromal symptoms, such as dizziness and sweating, significantly more often. The patients reported more injuries resulting from syncopal events and more previous syncopal events, and the prevalence of co-morbidity was greater among patients presenting negative findings during tilt testing. An asthenic-leptosomal physique was not confirmed as a risk factor for syncopal events as is the case for idiopathic arterial hypotension. However, patients with pathological reaction patterns during tilt table testing were significantly taller. This finding was detected for both females and males. No significant predictors were found in the electrocardiogram (ECG) patterns of patients showing syncope during tilt table testing. CONCLUSIONS: Frequency of prior syncope and prodromal symptoms, and increased body length with an otherwise good state of health influence the predictive value of tilt table testing for syncope diagnosis. In particular, if these factors are present, tilt table testing should be considered part of the diagnostic algorithm for soldiers with recurrent syncope.
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Gilfrich et al. (2015) conducted a cross-sectional in Syncope or pre-syncope (n=100). Positive head-up tilt table test (syncope induced) vs. Negative head-up tilt table test (asymptomatic) was evaluated on Mean number of previous syncopal events (p=<0.001). Patients who experienced syncope during head-up tilt testing had a significantly higher mean number of previous syncopal events (6.3 vs 2.4, p<0.001) and more frequently reported prodromal symptoms compared to asymptomatic patients.
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