April 24, 2007Pacing and Clinical Electrophysiology

Investigation of Various Types of Neurocardiogenic Response to Head‐Up Tilting by Extended Hemodynamic and Neurohumoral Monitoring

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Why the study?

Does extended monitoring during tilt-table testing provide additional information on the hemodynamic and vegetative state prior to neurocardiogenic syncope in patients with unexplained syncope?

Population

40 unselected consecutive patients with a history of unexplained syncope.

Design

Cohort

Authors

LNL NowakMünchen Klinik Bogenhausen FNFRANZ G. NOWAKMünchen Klinik Bogenhausen SJS. JankoUniversity of Bamberg

Discussion

Member takes

Implication

May aid syncope phenotyping; hypothesis-generating and should not yet change practice.

Structured PICO

Does extended monitoring during tilt-table testing provide additional information on the hemodynamic and vegetative state prior to neurocardiogenic syncope in patients with unexplained syncope?

Population

40 unselected consecutive patients with a history of unexplained syncope (7 excluded due to incomplete data, leaving 33 analyzed).

Intervention

Head-up tilt-table testing with extended monitoring including ECG, blood pressure, cardiac output, peripheral vascular resistance, contractility index by impedance cardiography, and epinephrine/norepinephrine plasma levels.

Outcome

Hemodynamic and neurohumoral presyncopal patterns (VASIS 1, 2B, 3, and orthostatic dysregulation).surrogate

Extended monitoring during tilt-table testing using impedance cardiography and plasma catecholamine measurements provides insight into distinct hemodynamic and neurohumoral presyncopal patterns in neurocardiogenic syncope.

Limitations

7 of 40 patients were unsuitable for analysis because of incomplete data sets

Cite This Study

Nowak et al. (2007) studied this question.

synapsesocial.com/papers/6a83fdcb062e2d56a83e9865 https://doi.org/10.1111/j.1540-8159.2007.00723.x

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Investigation of Various Types of Neurocardiogenic Response to Head‐Up Tilting by Extended Hemodynamic and Neurohumoral Monitoring

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Investigation of Various Types of Neurocardiogenic Response to Head‐Up Tilting by Extended Hemodynamic and Neurohumoral Monitoring

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider