Key result
The abstract outlines a study to test the effects of protein kinase C stimulation on whole heart electrophysiology in rabbit hearts, but provides no results.
Why the study?
Does protein kinase C activation affect cardiac repolarization and arrhythmogenesis in Langendorff-perfused rabbit hearts?
Does protein kinase C activation affect cardiac repolarization and arrhythmogenesis in Langendorff-perfused rabbit hearts?
No results reported on PKC effects in rabbit hearts; leaves open questions on repolarization and arrhythmogenesis for completed studies.
Aims Cardiac arrhythmias are still a major cause of mortality in western countries. Currently available antiarrhythmic drugs are limited by a low efficacy and proarrhythmic effects. The role of the protein kinase C (PKC) signalling pathway in arrhythmogenesis is still unclear. The goal of the present study was to test the effects of PKC stimulation on whole heart electrophysiology and its pro-/antiarrhythmic activity.
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Aydın et al. (2007) studied Cardiac arrhythmias. Protein kinase C (PKC) stimulation was evaluated on Whole heart electrophysiology and pro-/antiarrhythmic activity. The abstract outlines a study to test the effects of protein kinase C stimulation on whole heart electrophysiology in rabbit hearts, but provides no results.
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