Key result
Positive end-expiratory pressure (PEEP) ventilation at 15 cmH2O reduced venous admixture (QS/QT) to 13% compared to 21% with ZEEP in extremely obese patients during anaesthesia.
Why the study?
Does positive end-expiratory pressure (PEEP) alter oxygen transport and venous admixture in extremely obese patients during anaesthesia compared to zero end-expiratory pressure (ZEEP)?
Population
8 extremely obese patients (mean weight 136 kg)
Comparison
Anaesthesia with controlled ventilation and… vs Awake breathing air, and anaesthesia with zero…
Design
Case_series
Authors
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May reduce shunt but lower oxygen delivery in obese anesthesia patients; Level 5 data leaves optimal PEEP open for prospective trials.
Does positive end-expiratory pressure (PEEP) alter oxygen transport and venous admixture in extremely obese patients during anaesthesia compared to zero end-expiratory pressure (ZEEP)?
Absolute Event Rate: 13% vs 21%
In extremely obese patients during anaesthesia, PEEP ventilation significantly reduces venous admixture but also decreases cardiac output and overall oxygen availability.
J. Santesson (1976) studied Extreme obesity (n=8). Positive end-expiratory pressure (PEEP) ventilation vs. Zero end-expiratory pressure (ZEEP) ventilation was evaluated on Venous admixture (QS/QT). Positive end-expiratory pressure (PEEP) ventilation at 15 cmH2O reduced venous admixture (QS/QT) to 13% compared to 21% with ZEEP in extremely obese patients during anaesthesia.
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